Scientific Validation of Ethnomedicinal Use of Ipomoea batatas L. Lam. as Aphrodisiac and Gonadoprotective Agent against Bisphenol A Induced Testicular Toxicity in Male Sprague Dawley Rats
Table 6
Effect of I. batatas on endogenous antioxidant enzyme and NO levels.
Sample
CAT (U/mg protein)
POD (U/mg protein)
SOD (U/mg protein)
GSH (μM/mg protein)
Nitrite μM/mg protein)
Control
3.77±0.12
9.14±0.63
18.02±1.54
24.81±3.14
56.78±2.34
Vehicle (10% DMSO)
3.83±0.09
9.29±0.39
19.14±1.37
23.68±2.91
57.23±4.58
Sildenafil (10 mg/kg)
3.61±0.11
9.85±0.28
18.44±1.62
26.92±4.25
57.57±4.27
BPA (50 mg/kg)
1.71±0.07
3.41±0.14
8.19±1.56
12.71±2.84
83.54±3.12
IPT- EA (300 mg/kg)
3.66±0.12
8.94±0.32
17.59±1.44
25.65±4.72
58.12±2.89
IPT-M (300 mg/kg)
3.42±0.10
8.47±0.23
17.21±1.11
23.89±5.28
59.01±3.26
IPA-EA (300 mg/kg)
3.73±0.06
9.21±0.43
18.23±0.86
26.34±4.77
56.34±3.51
IPA-M (300 mg/kg)
3.67±0.13
8.85±0.58
17.46±1.28
24.88±3.69
58.68±2.59
BPA+IPT-EA (300 mg/kg)
3.21±0.15
7.71±0.32
15.88±1.18
19.66±4.28
67.25±1.98
BPA+IPT-EA (150 mg/kg)
2.98±0.10
5.92±0.40
13.11±0.74
17.17±2.18
73.33±1.39
BPA+IPT-M (300 mg/kg)
2.89±0.18
7.54±0.29
15.14±0.91
19.03±3.19
69.11±3.16
BPA+IPT-M (150 mg/kg)
2.56±0.11
5.80±0.38
12.84±1.21
16.60±2.10
75.01±2.59
BPA+IPA-EA (300 mg/kg)
3.12±0.27
7.99±0.43
16.67±1.45
20.23±2.14
63.38±2.74
BPA+IPA-EA (150 mg/kg)
2.82±0.21
7.01±0.21
14.54±1.58
18.22±2.43
68.76±2.10
BPA+IPA-M (300 mg/kg)
2.64±0.32
7.65±0.40
15.19±1.22
19.45±5.12
71.87±3.15
BPA+IPA-M (150 mg/kg)
2.37±0.15
6.05±0.40
12.96±1.06
17.05±3.45
76.56±2.01
All the data are represented as Mean±SD (n=7), means with different superscript letters in a column specify significant difference at P < 0.05. CAT, catalase, POD, peroxidase, SOD, superoxide dismutase, and GSH, glutathione.
