Identification of Key Transcription Factors AP-1 and AP-1-Dependent miRNAs Forming a Co-Regulatory Network Controlling PTEN in Liver Ischemia/Reperfusion Injury

Figure 4

Activation of AP-1 and AP-1 target genes in the process of liver ischemia/reperfusion (I/R) injury. (a) PTEN, p-c-JUN, GAPDH expression were examined by a western blot assay. (b, c) mRNA levels of AP-1 subunits (JUN and ATF3). (d, e) AP-1 target genes, including PTEN, MMP9. < 0.05,  < 0.01,  < 0.001 and  < 0.0001.

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