Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells

<div>Differentiation of MSCs into steroidogenic cells. (a) Schematic diagram of induction of steroidogenic cells from MSCs by introduction of SF-1/Ad4BP or LRH, and cAMP-treatment. (b) Differentiation of UCB-MSCs into luteal-like cells by SF-1/Ad4BP. RT-PCR analysis of each gene in each cell with or without 8-bromo-cAMP for 2 d. Lanes G–L are granulosa-luteal cells from women undergoing oocyte retrieval for<i> in vitro</i> fertilization.</div>

BioMed Research International

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Figure 2: Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells 