HIF-1-miR-219-SMC4 Regulatory Pathway Promoting Proliferation and Migration of HCC under Hypoxic Condition

Figure 1

SMC4 could regulate proliferation and migration of HCC cells under hypoxia. (a-b) Efficiency of SMC4 siRNA was verified on both protein and mRNA levels in HCC cells. n = 3, . (c) CCK-8 was used to detect cell viability of HCC cells with SMC4 siRNA and negative control under hypoxic condition. The value of 72 h was statistically analyzed. n = 7, . (d) Transwell assay was used to detect cell migration ability of HCC cells with SMC4 siRNA and negative control under hypoxic condition., n = 3, .

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