BioMed Research International / 2019 / Article / Tab 6

Research Article

Does Supersonic Shear Wave Elastography Help Differentiate Biliary Atresia from Other Causes of Cholestatic Hepatitis in Infants Less than 90 Days Old? Compared with Grey-Scale US

Table 6

Diagnostic performance of hepatic Young’s modulus values, typical grey scale ultrasound findings, and their combination to diagnose BA for all infants with cholestatic hepatitis.

P valueAUCP value vs SWE95%CISensitivitySpecificityPPVNPVAccuracy

SWE<0.0010.9370.894,0.97884.3%89.7%82.7%90.7%87.7%
TC<0.0010.863>0.050.787,0.93972.5%100%100%86.1%89.8%
AbGB<0.0010.94>0.050.895,0.98696.1%92.0%87.5%97.6%93.5%
SWE or TC<0.0010.899>0.050.839,0.95990.2%89.7%83.6%94.0%89.8%
SWE or AbGB<0.0010.908>0.050.857,0.959100%81.6%76.1%100%88.4%
TC or AbGB<0.0010.96>0.050.926,0.994100%92.0%87.9%100%94.9%
SWE or TC or AbGB<0.0010.908>0.050.857,0.959100%81.6%76.1%100%88.4%
SWE and TC<0.0010.833<0.050.751,0.91566.7%100%100%83.6%87.7%
SWE and AbGB<0.0010.902>0.050.849,0.97580.4%100%100%90.6%93.5%
TC and AbGB<0.0010.843<0.050.763,0.92368.6%100%100%84.5%88.4%
SWE and TC and AbGB<0.0010.814<0.050.728,0.89962.7%100%100%82.1%86.2%

compared with the AUC of SWE; or: in the parallel test; and, in the serial test; PPV: positive predictive value; NPV: negative predictive value.

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