Research Article

Expression and Clinical Significance of Decoy Receptor 3 in Acute-on-Chronic Liver Failure

Table 1

Comparison of clinical characteristics and biomarkers between ACLF and non-ACLF groups of patients.

ACLF (n=76)Non-ACLF (n=41)P value

Age (years)47.49 ± 15.2443.95 ± 14.900.230
Male (%)60 (78.95%)30 (73.17%)0.481
TBIL (μmol/L)311.99 ± 160.4679.96 ± 98.28<0.001
Albumin (g/L)30.65 ± 4.7337.47 ± 6.26<0.001
ALT (U/L)220(100.75--703.00)58 (32.00--227.00)<0.001
AST (U/L)207 (115.00--449.75)58(30.00--163.00)<0.001
γ-GT (U/L)117(78.25--210.50)59(27.00--135.00)0.001
WBC (×109/L)6.31(4.61--8.68)5.19 (3.77--6.41)0.007
N%69.80 ± 10.3957.21 ± 11.43<0.001
Platelet (×109/L)104.50 (63.00--135.75)140.5 (98.00--201.50)0.002
CRP(mg/L)18.54(9.80--18.54)12.44 (6.33--25.85)0.333
PCT(ng/mL)0.76(0.40--1.44)0.43 (0.21--0.78)0.011
PT(s)21.05(17.33-24.93)13.05 (12.25-14.88)<0.001
INR1.82 (1.49-2.24)1.12 (1.02-1.29)<0.001
Serum creatinine(umol/L)63.00 (50.25-70.00)64.20 (51.63-79.35)0.273
DcR3(ng/mL)0.97 (0.17- 2.32)0.21 (0.11-0.49)<0.001
Etiologies0.737
 HBV-related64(82.89%)33(80.49%)
 others9(13.16%)5(12.20%)
 Alcoholic3(3.95%)3(7.32%)

Data in this table were obtained upon admission and expressed as the number of patients (percentage), mean ± standard deviation, or mean (interquartile range).