BioMed Research International / 2019 / Article / Tab 1

Research Article

Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking

Table 1

Minimum inhibitory concentration (MIC), maximum fungicidal concentration (MFC) values, and MFC/MIC in μmol/mL in amides (1-10) against strains of the genus Candida.

AmidesCandida albicansCandida glabrataCandida kruseiCandida guilliermondii
(ATCC 90028)(ATCC 90030)(ATCC 34125) (207)
MICMFCMFC/MICMICMFCMFC/MICMICMFCMFC/MICMICMFCMFC/MIC

14.484.481++++++2.242.241
2+++++++++2.252.251
34.004.001++++++2.002.001
42.172.1712.172.1714.344.3412.172.171
53.883.881++++++1.941.941
61.811.8113.623.6213.623.6211.811.811
7+++3.683.681+++0.460.461
83.483.481+++++++++
9+++++++++1.661.661
10+++++++++1.571.571
Control medium------------
Nistatin0.000430.000430.000430.000430.000430.000430.000430.000430.000430.000430.000430.00043
Control microorganism++++++++++++

+: microorganism growth. -: no microorganism growth.

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