Research Article
Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking
Table 3
Bioactivity of the amides prepared against quantified strains of bacteria through the minimum inhibitory concentration (MIC) in μmol/mL.
| Amides | Pseudomonas aeruginosa | Pseudomonas aeruginosa | Staphylococcus aureus | Staphylococcus aureus | (ATCC 8027) | (102) | (ATCC 25925) | (47) |
| 1 | + | + | 4.48 | + | 2 | + | + | 4.50 | + | 3 | + | + | 4.01 | + | 4 | + | + | 4.34 | + | 5 | + | + | 3.88 | + | 6 | + | + | 3.62 | + | 7 | + | + | 3.68 | + | 8 | + | + | 3.48 | + | 9 | + | + | 3.32 | + | 10 | + | + | 3.14 | + | Control medium | - | - | - | - | Chloramphenicol | 0.3095 | 0.3095 | 0.3095 | 0.3095 | Control microorganism | + | + | + | + |
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+:microorganism growth. -: no microorganism growth.
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