Discovery and Validation of Serum MicroRNAs as Early Diagnostic Biomarkers for Prostate Cancer in Chinese Population

Table 3

ROC analysis of 5 miRNAs.

miRNA	AUC	Sensitivity (%)	Specificity (%)	95% CI	Cut-off value
miR-365a-3p	0.600	45.80	80.90	0.514-0.676	0.2062
miR-4286	0.610	67.50	52.78	0.527-0.688	3.7230
miR-424-5p	0.671	31.94	94.87	0.590-0.746	0.0135
miR-29b-3p	0.593	26.92	95.24	0.513-0.669	0.1415
miR-27a-3p	0.601	28.21	97.18	0.518-0.681	2.1588

Cut-off value: the value was relative expression level of targeted miRNA compared with expression level of miR-1228-3p.