Combined Analysis of the Aberrant Epigenetic Alteration of Pancreatic Ductal Adenocarcinoma

Table 2

Prognostic hypermethylation/hypomethylation genes for PDAC in Kaplan–Meier survival analysis and univariate Cox regression analysis.

Gene	value (KM)	HR	Low 95%	High 95%	value (Cox)
ID4	0.042672	3.630678	0.520149	25.34241	0.193383
CBLN4	0.023498	8.850718	1.048889	74.68398	0.045088
NOL4	0.004024	4.335809	0.684543	27.46246	0.119342
ZSCAN23	0.025771	2.565136	0.291866	22.54433	0.395617
ZNF208	0.027825	4.378881	0.610815	31.39183	0.14171
TPTEP1	0.031211	9.031061	0.565839	144.1401	0.119457
CTD-2554C21.2	0.02653	3.226591	0.659874	15.77709	0.148008
HMGCLL1	0.032094	5.418468	0.99398	29.53761	0.050821
TBX18	0.013916	1.719498	0.399601	7.399053	0.466623
CDO1	0.002445	9.153049	1.051298	79.69033	0.044934
GJD2	0.03223	2.621186	0.475785	14.44059	0.268377
KCNJ8	0.047027	2.946227	0.607266	14.29399	0.179935
ZNF382	0.025139	2.887076	0.625426	13.32725	0.174279
RP11-748H22.1	0.021448	2.767153	0.603237	12.69342	0.190326
AC005498.3	0.037114	3.33757	0.887535	12.55091	0.074517
KCNA3	0.017149	1.742724	0.2681	11.3282	0.560838
TLL1	0.010797	5.624124	0.745679	42.41878	0.093876
ZNF454	0.047434	2.430637	0.414374	14.25765	0.325139
GRIA2	0.007244	4.082081	0.778325	21.40929	0.096198
SNAP91	0.000726	4.182435	0.957687	18.26563	0.057108
PHYHIPL	6.50E-05	4.99462	0.648914	38.44306	0.122433
PAX6	0.045649	3.477117	0.489556	24.69657	0.212806
TRIM58	0.014099	2.686691	0.452754	15.9431	0.276686
RP11-760D2.5	0.010799	3.659025	0.898893	14.89439	0.070119
PABPC5	0.029366	2.600122	0.768849	8.79319	0.124263
PSMG3	0.024383	0.070082	0.005646	0.869985	0.038608
BX470102.3	0.00414	0.056038	0.003752	0.836902	0.036704
CTD-2330K9.2	0.014257	0.234518	0.064259	0.855889	0.028124
RP11-734K21.5	0.030528	0.143102	0.033485	0.611557	0.008702
GDPD3	0.007174	0.056417	0.005122	0.621427	0.018844
C19orf33	0.042501	0.239202	0.03509	1.630583	0.144101
MOGAT2	0.006182	0.040403	0.00416	0.392444	0.005669
RP5-1142J19.1	0.025301	0.111422	0.015353	0.808636	0.030006
C11orf53	0.013738	0.265261	0.031938	2.20313	0.219203
LIPH	0.008497	0.087046	0.010817	0.700467	0.021758