Melittin Inducing the Apoptosis of Renal Tubule Epithelial Cells through Upregulation of Bax/Bcl-2 Expression and Activation of TNF-α Signaling Pathway

Figure 6

The expression of TNF-α in HK-2 cells. The mRNA expression of TNF-α in HK-2 cells (a). P (compared with the control): <0.01. The protein expression of TNF-α in HK-2 cells detected by simple Western assays (b). A: the control group, B: the melittin group, C: the TNF-α group, D: the melittin+TNF-α group. P (compared with the control): <0.05, <0.01. The protein expression of TNF-α in HK-2 cells detected by IF stains (c). Magnification×200. P(compared with the control): <0.01, <0.001. The serum level of TNF-α in mice (d). P(compared with the control): <0.05.

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