Orostachys japonicus A. Berger Extracts Induce Immunity-Enhancing Effects on Cyclophosphamide-Treated Immunosuppressed Rats

Figure 3

OJ extracts increased immunity-associated plasma cytokine levels. (a) Plasma TNF-α level. (b) Plasma IFN-γ level. (c) Plasma IL-2 level. Values represent mean ± SD (n = 8). Bars not sharing common letter represent statistically significant difference from each other (p < 0.05). (d) Representative images of sectioned spleens: (A) normal (no treatment), (B) only CY-treated, (C) OJWE-low, OJWE administered at 100 mg/kg with CY treatment; (D) OJWE-high, OJWE administered at 1,000 mg/kg with CY treatment; (E) OJEE-low, OJEE administered at 100 mg/kg with CY treatment; and (F) OJEE-high, OJEE administered at 1,000 mg/kg with CY treatment. Scale bar in A, 100 μm, applicable to B–F. CV, central vein; MZ, marginal zone; RP, red pulp; WP, white pulp.

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