Research Article

Identification of Key Pathways and Genes of Acute Respiratory Distress Syndrome Specific Neutrophil Phenotype

Table 1

The top 30 hub genes of the PPI network in GSE76293. logFC: log2 fold change between two experimental conditions. adj.P.Val: p value after adjustment for multiple testing.

Gene symbolDegreelogFCadj.P.Val

GAPDH1061.282.69E-06
AKT1105-1.236.93E-05
RIPK4102-1.623.42E-04
TOP2A870.973.44E-03
MAPK14691.501.74E-07
MAPK868-0.972.15E-03
CXCL867-2.121.97E-03
SMARCA466-0.627.63E-03
PIK3CB600.653.56E-03
APP551.374.14E-03
CREB151-0.686.18E-03
JAK2470.955.29E-05
CD44431.822.85E-06
HDAC4420.971.66E-05
PTGS239-1.475.15E-03
H2AFV39-0.682.36E-03
MMP9370.692.75E-04
BCL2L1370.843.26E-03
SKP236-0.695.53E-03
POLR2I35-0.692.77E-03
NDE135-0.728.75E-04
ITGAM340.795.92E-05
SNU1334-0.783.66E-03
CSF1R33-2.101.08E-05
HIST1H2BK320.601.05E-04
MIB231-0.735.11E-04
CDKN3300.896.48E-04
UBE2D429-0.591.51E-03
NDC8029-1.136.52E-04