The Polymorphism rs17525495 of LTA4H Is Associated with Susceptibility of Crohn’s Disease instead of Intestinal Tuberculosis in a Chinese Han Population
Table 2
The genotype and allele frequency distribution of rs17525495 in ITB, CD, and HC groups.
(a)
Genotype & Allele
HC
ITB
OR (95% CI)
P
OR (95% CI)
CC
336
72
1.00
1.00
CT
311
58
0.87(0.60-1.27)
0.472
0.88(0.60-1.28)
0.495
TT
53
18
1.59(0.88-2.87)
0.127
1.44(0.79-2.63)
0.234
C
983
202
1.00
1.00
T
417
94
1.10(0.84-1.44)
0.502
1.07(0.81-1.41)
0.630
(b)
Genotype & Allele
HC
CD
OR (95% CI)
P
OR (95% CI)
CC
336
57
1.00
1.00
CT
311
69
1.31(0.89-1.92)
0.170
1.31(0.89-1.92)
0.178
TT
53
19
2.11(1.17-3.83)
0.014
1.92(1.05-3.51)
0.034
C
983
183
1.00
1.00
T
417
107
1.38(1.06-1.80)
0.017
1.34(1.03-1.75)
0.032
(c)
Genotype & Allele
ITB
CD
OR (95% CI)
P
OR (95% CI)
P
CC
72
57
1.00
1.00
CT
58
69
1.50(0.92-2.50)
0.105
1.53(0.93-2.53)
0.094
TT
18
19
1.33(0.64-2.77)
0.441
1.26(0.60-2.66)
0.539
C
202
183
1.00
1.00
T
94
107
1.26(0.89-1.77)
0.190
1.24(0.88-1.75)
0.226
The major genotype or allele was used as baseline. Adjusted for gender, age, smoking, and drinking history. Bold italics indicate the statistical significance (P < 0.05).
