Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota

Figure 5

Treatment with XQLT prevented inflammation in rats with heart failure with preserved ejection fraction (HFpEF). (a) The inflammation-associated protein expression of MCP-1, TNF-α, and IL-6 in the left ventricle was assessed using western blot analysis and was compared with that in the NS group. (b) HE staining of the left ventricle is shown; inflammatory cell infiltration was assessed by analysis of the HE staining. The data are presented as the mean±SD (n=6 rats per group). p < 0.05 and p < 0.01 compared with the NS group; p <0.05 and p <0.01 compared with the HS group.

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