Micronized Palmitoylethanolamide-Polydatin Reduces the Painful Symptomatology in Patients with Interstitial Cystitis/Bladder Pain Syndrome

Table 2

Effect of mPEA-Pol on Interstitial Cystitis Symptoms and Problem Index (ICSI and ICPI) evaluated with O’Leary-Sant questionnaire in IC/BPS patients.

	Time (months)
	0	2	4	6
ICSI	11.0 ± 0.8	9.9 ± 0.8	8.3 ± 0.9	8.9 ± 0.9	0.0110
ICPI	10.3 ± 0.7	9.1 ± 0.8	8.4 ± 0.9	7.5 ± 0.8	0.0014
Total	21.3 ± 1.4	19.0 ± 1.6	16.8 ± 1.7	16.5 ± 1.7	0.0028

Data are expressed as means ± SE; n = 32 at baseline and two months; 29 and 26 at four and six months, respectively. refers to score changes over time.