Micronized Palmitoylethanolamide-Polydatin Reduces the Painful Symptomatology in Patients with Interstitial Cystitis/Bladder Pain Syndrome

Table 3

Effect of mPEA-POL on the pelvic pain and urgency/frequency symptom evaluated with PUF scale in IC/BPS patients.

	Time (months)
	0	2	4	6
Symptom	12.6 ± 0.8	11.0 ± 1.0	10.1 ± 1.0	9.7 ± 1.0	0.0163
Bother	11.0 ± 0.7	9.2 ± 0.8	8.0 ± 0.7	7.7 ± 0.9	0.0005
Total	23.5 ± 1.4	20.2 ± 1.6	18.1 ± 1.6	17.4 ± 1.9	0.0019

Data are expressed as means ± SE; n = 32 at baseline and two months; 29 and 26 at four and six months, respectively. refers to score changes over time.