Simultaneous Determination of Six Uncaria Alkaloids in Mouse Blood by UPLC–MS/MS and Its Application in Pharmacokinetics and Bioavailability

Table 2

Regression equation and correlation coefficient for rhynchophylline, isorhynchophylline, corynoxeine, isocorynoxeine, hirsutine, and hirsuteine in mouse blood (; ).

Compound	Linear range (ng/mL)	Regression equation	Correlation coefficient
Rhynchophylline	1-1000		0.9988
Isorhynchophylline	1-1000		0.9972
Corynoxeine	1-1000		0.9990
Isocorynoxeine	1-1000		0.9992
Hirsutine	1-1000		0.9976
Hirsuteine	1-1000		0.9960