Research Article

TMT-Based Quantitative Proteomic Analysis Identification of Integrin Alpha 3 and Integrin Alpha 5 as Novel Biomarkers in Pathogenesis of Acute Aortic Dissection

Figure 1

Experimental flowchart. The aortic arch tissues of 5 patients with AAD were extracted during surgery. The peptides labelled with TMT were prepared, and a MS/MS analysis was performed. The proteomic data were analyzed, and the DAPs were selected and verified by immunohistochemistry.