Research Article

Transcriptomic Analysis of Glioma Based on IDH Status Identifies ACAA2 as a Prognostic Factor in Lower Grade Glioma

Table 1

The top 20 metabolic genes based on the value of MDG.

Gene nameGene full nameMean decrease Gini

B3GNT7Beta-1,3-N-acetylglucosaminyltransferase 710.34689677
ACSS3Acyl-CoA synthetase short-chain family member 37.909816
DCTDdCMP deaminase7.36251499
PPCSPhosphopantothenoylcysteine synthetase6.42529875
PLA2G5Phospholipase A2 group V6.36536675
PIPOXPipecolic acid and sarcosine oxidase6.12854856
ACAA2Acetyl-CoA acyltransferase 25.55485439
GALNT13Polypeptide N-acetylgalactosaminyltransferase 135.54486482
OPLAH5-Oxoprolinase, ATP hydrolysis5.04530335
HS3ST3B1Heparan sulfate-glucosamine 3-sulfotransferase 3B14.89715727
CHST6Carbohydrate sulfotransferase 64.58671345
PNPLA4Patatin-like phospholipase domain containing 44.40125265
FUCA2Alpha-L-fucosidase 23.22170785
BCAT1Branched chain amino acid transaminase 13.00358464
GLUD1Glutamate dehydrogenase 12.85948492
CBR1Carbonyl reductase 12.84089168
GALMGalactose mutarotase2.44693901
B3GNT5Beta-1,3-N-acetylglucosaminyltransferase 52.15619286
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 22.15531693
CA3Carbonic anhydrase 32.02087863