Research Article
Expression and Genetic Polymorphisms of ERCC1 in Chinese Han Patients with Oral Squamous Cell Carcinoma
Table 2
Frequencies of genotypes and alleles of ERCC1 polymorphisms in OSCC patients and controls.
| SNP | Genotype allele | OSCC () | Controls () | value | | OR | 95% CI |
| rs11615 | CC | 60 | 111 | 0.221 | NS | 0.745 | 0.464 | 1.195 | CT | 48 | 66 | 0.256 | NS | 1.320 | 0.817 | 2.133 | TT | 5 | 7 | 0.792 | NS | 1.171 | 0.362 | 3.781 | C | 168 | 288 | 0.271 | NS | 0.805 | 0.546 | 1.186 | T | 58 | 80 | 0.271 | NS | 1.243 | 0.843 | 1.832 |
| rs3212948 | CC | 5 | 7 | 0.792 | NS | 1.171 | 0.362 | 3.781 | CG | 48 | 66 | 0.256 | NS | 1.320 | 0.817 | 2.133 | GG | 60 | 111 | 0.221 | NS | 0.745 | 0.464 | 1.195 | C | 58 | 80 | 0.271 | NS | 1.243 | 0.843 | 1.832 | G | 168 | 288 | 0.271 | NS | 0.805 | 0.546 | 1.186 |
| rs3212961 | AA | 22 | 42 | 0.495 | NS | 0.817 | 0.458 | 1.459 | AC | 60 | 91 | 0.542 | NS | 1.157 | 0.724 | 1.849 | CC | 31 | 51 | 0.958 | NS | 0.986 | 0.584 | 1.666 | A | 104 | 175 | 0.716 | NS | 0.940 | 0.674 | 1.310 | C | 122 | 193 | 0.716 | NS | 1.064 | 0.763 | 1.483 |
| rs735482 | AA | 34 | 57 | 0.872 | NS | 0.959 | 0.576 | 1.596 | AC | 58 | 83 | 0.297 | NS | 1.283 | 0.802 | 2.052 | CC | 21 | 44 | 0.281 | NS | 0.726 | 0.406 | 1.301 | A | 126 | 197 | 0.598 | NS | 1.094 | 0.784 | 1.526 | C | 100 | 171 | 0.598 | NS | 0.914 | 0.655 | 1.276 |
|
|
CI: confidence intervals; OR: odds ratios; NS: not significant; : the Bonferroni correction values. |