Review Article

A Comprehensive Review of Cutaneous Manifestations Associated with COVID-19

Table 2

Classification and characteristics of the cutaneous lesions reported in association with COVID-19.

Cutaneous manifestation (total number of reported cases)Number of patientsAge, mean (range) (years)SexCountryLocation of skin lesionsDermatologic symptomsPhase of COVID-19 in which skin lesions appearedMethod of COVID-19 diagnosis

Maculopapular rash20060.6 (6-89)F: 102
M: 82
N/M: 16
Spain: 176
Italy: 17
France: 4
USA: 2
Thailand: 1
Trunk: 14
Generalized (erythroderma): 8
Face & upper body: 2
N/M: 176
Asymptomatic: 64
Itching: 104
Burning: 10
Pain: 4
N/M: 18
Prodromal: 9
Active: 131
Convalescence: 60
146 cases were confirmed by PCR. Others were not tested or N/M.

Urticaria8447.6 (2 months–71 years)
N/M: 5
F: 52
M: 27
N/M: 5
Spain: 74
Italy: 4
France: 3
Belgium: 2
Thailand: 1
Trunk: 3
Generalized: 4
Face & upper body: 3
N/M: 73
Asymptomatic: 9
Itching: 73
Burning: 1
Pain: 1
Prodromal: 5
Active: 52
Convalescence: 25
N/M: 2
57 cases were confirmed by PCR. Others were not tested or N/M.

Chilblain8131.76 (14-48)F: 53
M: 25
N/M: 3
Spain: 72
Italy: 4
France: 3
Kuwait: 2
Fingers: 2
Heel & toes: 79
Asymptomatic: 24
Itching: 22
Burning: 11
Pain: 26
Prodromal: 5
Active: 26
Convalescence: 42
Asymptomatic carrier of COVID-19: 8
31 cases were confirmed by PCR. Others were not tested or N/M.

Vesicular rash61Not reportableF: 26
M: 31
N/M: 4
Spain: 26
Italy: 35
Trunk: 26 (2 of them localized & herpetiform)
N/M: 35
Asymptomatic: 20
Itching: 34
Burning: 2
Pain: 3
N/M: 2
Prodromal: 5
Active: 46
Convalescence: 10
41 cases were confirmed by PCR. Others were not tested or N/M.

Livedo reticularis2362.5F: 11
M: 12
Spain: 21
USA: 2
Lower limb: 2 (unilateral)
N/M: 21
Asymptomatic: 17
Itching: 3
Burning: 2
Pain: 1
Prodromal: 1
Active: 19
Convalescence: 3
19 cases were confirmed by PCR. Others were not tested or N/M.

Petechiae21 patient: 48
1 patient: N/M
M: 1
N/M: 1
Spain: 1
Thailand: 1
Lower half of the body: 1
N/M: 1
N/M
Itching
Prodromal: 1
Active: 1
Both cases were confirmed by PCR.

M: male; F: female; N/M: not mentioned; PCR: polymerase chain reaction.