Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats

<div>PLS-DA-derived (a) score plot and (b) loading score plot obtained using <sup>1</sup>H-NMR spectra of serum samples in Sprague-Dawley rats from the lean (LN), obese (OB), obese+saffron extract 80 mg/kg (OBSF80), and obese+crocin 80 mg/kg (OBCR80) groups after eight weeks of the treatment period (<span class="nowrap"><svg height="14.8642pt" id="M33" style="vertical-align:-3.272799pt" version="1.1" viewbox="-0.0498162 -11.5914 80.0741 14.8642" width="80.0741pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M610 18C585 26 567 34 540 68C517 97 499 128 476 171C452 215 425 276 413 304C496 332 570 394 570 494C570 555 545 595 509 619S419 650 364 650H139L133 622C216 615 219 612 203 527L129 132C112 40 105 36 23 28L17 0H279L285 28C199 34 194 40 211 132L239 284H284C320 284 334 275 351 236C374 182 394 140 420 93C459 23 495 -1 592 -8H600L610 18ZM480 485C480 424 449 372 403 342C374 323 338 316 293 316H245L291 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BioMed Research International

fig4

Figure 4

Figure 4: Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats 