Comparison of Predictive Powers for Mortality between Systemic Vascular Resistance Index and Serum Lactate in Children with Persistent Catecholamine-Resistant Shock
Table 1
Demographics and initial hemodynamic parameters between the survivors and 28-day mortality group.
Variables
Survival ()
28-day mortality ()
value
Age mean (SD), years
12 (4.7)
12.4 (3.3)
0.877
Sex (male), (%)
5 (41.6)
8 (57.1)
PRISM, median (IQR)
8.8 (2-19)
11.1 (7-13)
0.188
Site of infection, (%)
0.39
Central nervous system
0
3 (21.4)
Blood stream
5 (41.6)
6 (42.8)
Respiratory
4 (33.3)
3 (21.4)
Urologic
1 (8.3)
0
Abdominal
1 (8.3)
0
Others
1 (8.3)
2 (14.2)
Culture positive, (%)
10 (83.3)
11 (78.5)
0.843
Pathogen, (%)
0.862
Gram positive
4 (33.3)
4 (28.5)
Gram negative
5 (41.6)
5 (35.7)
Fungus
1 (8.3)
1 (7.1)
Virus
0 (0)
1 (7.1)
Unknown
2 (16.6)
3 (21.4)
Used vasoactive-inotropic agents, (%)
Dopamine
11 (91.6)
14 (100)
0.921
Epinephrine
9 (75)
13 (92.8)
0.473
Norepinephrine
4 (33.3)
7 (50)
0.642
Dobutamine
1 (8.3)
7 (50)
0.068
Milrinone
9 (75)
8 (57.1)
0.597
Vasopressin
0
1 (7.1)
0.924
Outcomes ()
ICU stay (days)
25.9 (18.7)
13.8 (9.4)
0.031
Length of stay (days)
39.1 (30.1)
21.3 (15.7)
0.099
Cardiac characteristics before PiCCO implantation ()
Vasoactive-inotropic scores
30.7 (13.9)
65.6 (64.9)
0.027
Heart rate (beats/min)
118 (32)
143 (28)
0.092
Mean arterial pressure (mmHg)
82.5 (16.7)
53.4 (13.8)
<0.001
Lactate (mg/dL)
32.3 (14)
74.2 (46.9)
0.005
Initial hemodynamic parameters ()
Cardiac output
CO (L/min)
3.9 (1.52)
4.5 (1.5)
0.273
Cardiac contractility
CI (L/min/m2)
3.7 (1.1)
3.9 (1)
0.603
GEF (%)
32.3 (11.1)
27.2 (8.7)
0.356
CFI (I/min)
9.2 (3.1)
9.1 (3.2)
1
Preload parameters
GEDVI (mL/m2)
431.7 (161.7)
447.1 (150.9)
0.823
ITBVI (mL/m2)
539.1 (202.2)
558.6 (188.8)
0.823
SVV (%)
10.3 (3.4)
17.2 (6.9)
0.006
Afterload parameters
SVRI (dyn·s·cm-5·m2)
1591.2 (409.5)
849 (286.8)
<0.001
Lung parameters
EVLWI (mL/m2)
10.6 (4.4)
12.2 (6.4)
0.507
PVPI
2.9 (0.9)
3.3 (1)
0.326
ICU: intensive care unit; CO: cardiac output; CI: cardiac index; GEF: global ejection fraction; CFI: cardiac function index; GEDVI: global end-diastolic volume index; ITBVI: intrathoracic blood volume index; SVV: stroke volume variation; SVRI: systemic vascular resistance index; EVLWI: extravascular lung water index; PVPI: pulmonary vascular permeability index. Statistical significance was set at p < 0.05.
