Research Article

Prognostic Nomograms for Primary High-Grade Glioma Patients in Adult: A Retrospective Study Based on the SEER Database

Table 1

Baseline characteristics of glioma patients from SEER database.

Patient characteristicsAll patientsTraining setValidation set
N =6395N =3166N =3229
No. of patients(%)No. of patients(%)No. of patients(%)

Age(years)
  <562328 (36.4)1156 (36.5)1172 (36.3)
 56-753115 (48.7)1543 (48.7)1572 (48.7)
  >75952 (14.9)467 (14.8)485 (15.0)
Gender
 Male3754 (58.7)1850 (58.4)1904 (59.0)
 Female2641 (41.3)1316 (41.6)1325 (41.0)
Race
 White5788 (90.5)2882 (91.0)2906 (90.0)
 Black320 (5.0)153 (4.8)167 (5.2)
 Othera287 (4.5)131 (4.1)156 (4.8)
Marital status
 Married4204 (65.7)2099 (66.3)2105 (65.2)
 Single945 (14.8)464 (14.7)481 (14.9)
 Separated/Divorced633 (9.9)296 (9.3)337 (10.4)
 Widowed613 (9.6)307 (9.7)306 (9.5)
Grade
 GradeIII603 (9.4)292 (9.2)311 (9.6)
 GradeIV5792 (90.6)2874 (90.8)2918 (90.4)
Laterality
 Left2798 (43.8)1388 (43.8)1410 (43.7)
 Right2861 (44.7)1425 (45.0)1436 (44.5)
 Not a paired site736 (11.5)353 (11.1)383 (11.9)
Site
 C71.1Frontal lobe2100 (32.8)1050 (33.2)1050 (32.5)
 C71.2Temporal lobe1719 (26.9)838 (26.5)881 (26.3)
 C71.3Parietal lobe1194 (18.7)596 (18.8)598 (18.5)
 C71.4Occipital lobe280 (4.4)139 (4.4)141 (4.4)
 C71.8Overlapping lesion1102 (17.2)543 (17.2)559 (17.3)
Histological
 Mixed glioma368 (5.8)174 (5.5)194 (6.0)
 Astrocytoma321 (5.0)171 (5.4)150 (4.6)
 Glioblastoma5622 (87.9)2788 (88.1)2834 (87.8)
 Oligodendroglioma84 (1.3)33 (1.0)51 (1.6)
Size(mm)
  <26855 (13.4)439 (13.9)416 (12.9)
 27-442144 (33.5)1045 (33.0)1099 (34.0)
  >443396 (53.1)1682 (53.1)1714 (53.1)
Surgery
 No surgery1123 (17.6)580 (18.3)543 (16.8)
 Subtotal resection1875 (29.3)930 (29.4)945 (29.3)
 Gross resection993 (15.5)496 (15.7)497 (15.4)
 Resection of lobe of brain2404 (37.6)1160 (36.6)1244 (38.5)
Radiotherapy
 Yes4897 (76.6)2422 (76.5)2475 (76.6)
 No/unknown1498 (23.4)744 (23.5)754 (23.4)
Chemotherapy
 Yes4402 (68.8)2172 (68.6)2230 (69.1)
 No/unknown1993 (31.2)994 (31.4)999 (30.9)
Radiation sequence with surgery
 Prior to surgery22 (0.3)13 (0.4)9 (0.3)
 After surgery4171 (65.2)2042 (64.5)2129 (65.9)
 Before and after28 (0.4)12 (0.4)16 (0.5)
 Unknown2174 (34.0)1099 (34.7)1075 (33.3)

aIncluding American Indian/Alaskan native and Asian/Pacific islander.