Research Article
Prognostic Nomograms for Primary High-Grade Glioma Patients in Adult: A Retrospective Study Based on the SEER Database
Table 1
Baseline characteristics of glioma patients from SEER database.
| Patient characteristics | All patients | Training set | Validation set | N =6395 | N =3166 | N =3229 | No. of patients(%) | No. of patients(%) | No. of patients(%) |
| Age(years) | | | | <56 | 2328 (36.4) | 1156 (36.5) | 1172 (36.3) | 56-75 | 3115 (48.7) | 1543 (48.7) | 1572 (48.7) | >75 | 952 (14.9) | 467 (14.8) | 485 (15.0) | Gender | | | | Male | 3754 (58.7) | 1850 (58.4) | 1904 (59.0) | Female | 2641 (41.3) | 1316 (41.6) | 1325 (41.0) | Race | | | | White | 5788 (90.5) | 2882 (91.0) | 2906 (90.0) | Black | 320 (5.0) | 153 (4.8) | 167 (5.2) | Othera | 287 (4.5) | 131 (4.1) | 156 (4.8) | Marital status | | | | Married | 4204 (65.7) | 2099 (66.3) | 2105 (65.2) | Single | 945 (14.8) | 464 (14.7) | 481 (14.9) | Separated/Divorced | 633 (9.9) | 296 (9.3) | 337 (10.4) | Widowed | 613 (9.6) | 307 (9.7) | 306 (9.5) | Grade | | | | GradeIII | 603 (9.4) | 292 (9.2) | 311 (9.6) | GradeIV | 5792 (90.6) | 2874 (90.8) | 2918 (90.4) | Laterality | | | | Left | 2798 (43.8) | 1388 (43.8) | 1410 (43.7) | Right | 2861 (44.7) | 1425 (45.0) | 1436 (44.5) | Not a paired site | 736 (11.5) | 353 (11.1) | 383 (11.9) | Site | | | | C71.1Frontal lobe | 2100 (32.8) | 1050 (33.2) | 1050 (32.5) | C71.2Temporal lobe | 1719 (26.9) | 838 (26.5) | 881 (26.3) | C71.3Parietal lobe | 1194 (18.7) | 596 (18.8) | 598 (18.5) | C71.4Occipital lobe | 280 (4.4) | 139 (4.4) | 141 (4.4) | C71.8Overlapping lesion | 1102 (17.2) | 543 (17.2) | 559 (17.3) | Histological | | | | Mixed glioma | 368 (5.8) | 174 (5.5) | 194 (6.0) | Astrocytoma | 321 (5.0) | 171 (5.4) | 150 (4.6) | Glioblastoma | 5622 (87.9) | 2788 (88.1) | 2834 (87.8) | Oligodendroglioma | 84 (1.3) | 33 (1.0) | 51 (1.6) | Size(mm) | | | | <26 | 855 (13.4) | 439 (13.9) | 416 (12.9) | 27-44 | 2144 (33.5) | 1045 (33.0) | 1099 (34.0) | >44 | 3396 (53.1) | 1682 (53.1) | 1714 (53.1) | Surgery | | | | No surgery | 1123 (17.6) | 580 (18.3) | 543 (16.8) | Subtotal resection | 1875 (29.3) | 930 (29.4) | 945 (29.3) | Gross resection | 993 (15.5) | 496 (15.7) | 497 (15.4) | Resection of lobe of brain | 2404 (37.6) | 1160 (36.6) | 1244 (38.5) | Radiotherapy | | | | Yes | 4897 (76.6) | 2422 (76.5) | 2475 (76.6) | No/unknown | 1498 (23.4) | 744 (23.5) | 754 (23.4) | Chemotherapy | | | | Yes | 4402 (68.8) | 2172 (68.6) | 2230 (69.1) | No/unknown | 1993 (31.2) | 994 (31.4) | 999 (30.9) | Radiation sequence with surgery | | | | Prior to surgery | 22 (0.3) | 13 (0.4) | 9 (0.3) | After surgery | 4171 (65.2) | 2042 (64.5) | 2129 (65.9) | Before and after | 28 (0.4) | 12 (0.4) | 16 (0.5) | Unknown | 2174 (34.0) | 1099 (34.7) | 1075 (33.3) |
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aIncluding American Indian/Alaskan native and Asian/Pacific islander.
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