Research Article
L1CAM High Expression Associates with Poor Prognosis in Glioma but Does Not Correlate with C11orf95-RELA Fusion
Table 1
Clinicopathological characteristics in relation to L1CAM expression.
| | Total | L1CAM | L1CAM | | Negative | Positive |
| Total | 565 | 456 | (80.71%) | 109 | (19.29%) | | Gender | | | | | | 0.400 | Male | 323 | 259 | (80.19%) | 64 | (19.81%) | | Female | 242 | 197 | (81.40%) | 45 | (18.60%) | | Age | | | | | | 0.006 | <=45 | 343 | 289 | (84.26%) | 54 | (15.74%) | | >45 | 222 | 167 | (75.23%) | 55 | (24.77%) | | Location | | | | | | 0.583 | Supratentorial | 517 | 413 | (79.88%) | 104 | (20.12%) | | Subtentorial | 48 | 43 | (89.58%) | 5 | (10.42%) | | WHO grade | | | | | | 0.371 | Low-grade (I and II) | 197 | 161 | (81.73%) | 36 | (18.27%) | | High-grade (III and IV) | 368 | 295 | (80.16%) | 73 | (19.84%) | | IDH | | | | | | 0.260 | Mutated | 240 | 196 | (81.67%) | 44 | (18.33%) | | Wildtype | 325 | 260 | (80.00%) | 65 | (20.00%) | | ATRX | | | | | | 0.003 | Mutated | 239 | 215 | (89.96%) | 24 | (10.04%) | | Wildtype | 326 | 241 | (73.93%) | 85 | (26.07%) | | P53 | | | | | | 0.181 | <=10% | 245 | 193 | (78.78%) | 52 | (21.22%) | | >10% | 320 | 263 | (82.19%) | 57 | (17.81%) | | Ki67 | | | | | | 0.007 | <=10% | 194 | 168 | (86.60%) | 26 | (13.40%) | | >10% | 371 | 288 | (77.63%) | 83 | (22.37%) | |
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