L1CAM High Expression Associates with Poor Prognosis in Glioma but Does Not Correlate with C11orf95-RELA Fusion

Table 2

Univariate and multivariate analysis for overall survival in glioma.

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Gender (male)	1.176 (0.941~1.470)	0.155
Age (years >45)	1.808 (1.449~2.256)	<0.001	1.182 (0.926-1.509)	0.178
Location (Supratentorial)	1.172 (0.921~1.493)	0.197
WHO grade (high)	2.582 (1.993~3.343)	<0.001	1.662 (1.182-2.337)	0.003
IDH (mutated)	0.336 (0.262~0.432)	<0.001	0.427 (0.327-0.557)	<0.001
ATRX (mutated)	1.104 (0.881~1.383)	0.392
P53 (>10%)	1.315 (1.047~1.652)	0.018	1.216 (0.949-1.560)	0.123
Ki67 (>10%)	2.464 (1.907~3.182)	<0.001	1.269 (0.901-1.786)	0.173
L1CAM (positive)	2.503 (1.932~3.241)	<0.001	1.528 (1.984-3.412)	<0.001