BioMed Research International / 2020 / Article / Fig 2

Research Article

Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer

Figure 2

Phloretin treatment induced morphological changes and decreased cell viability in prostate cancer cells. (a) After treating with different concentrations of phloretin (0, 20, 50, and 100 μM) in WPMY-1, LNCaP, CWR22Rv1, PC-3, and DU145 cells ( cells/well) for 24 h, cell morphological changes were observed and photographed with microscope (Nikon microscope, Japan) under 10x magnification. (b, c) WPMY-1, LNCaP, CWR22Rv1, PC-3, and DU145 cells were treated with different concentrations of phloretin (0, 20, 50, and 100 μM) for 24 h, and then cells were harvested for MTT and CCK-8 assays, respectively. The percentages of cell viabilities were calculated by comparing with control samples. , .
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