Research Article

Efficacy and Safety of Lamivudine or Telbivudine in Preventing Mother-to-Child Transmission of Hepatitis B Virus: A Real-World Study

Table 1

Baseline clinical characteristics of pregnant women infected with hepatitis B virus among three groups.

VariableLAM group ()LdT group ()Control group ()

Age (years)0.107
Primigravida (, %)290 (79.9)1018 (79.3)765 (78.2)0.732
HBeAg positive (, %)351 (96.7)1257 (98.0)962 (98.4)0.159
Treatment experienced (, %)10 (2.8)38 (3.0)29 (3.0)0.967
ALT (U/L)42 (8–572)37 (6–493)32 (5–404)<0.001
Rate of abnormal ALT (%)76 (20.9)290 (22.6)184 (18.8)0.090
HBV DNA (log10 IU/mL)<0.001

Values presented as or median (range), unless otherwise noted. ALT: alanine aminotransferase; HBeAg: hepatitis B e antigen; HBV: hepatitis B virus.