Research Article

Associations between NLRC4 Gene Polymorphisms and Autoimmune Thyroid Disease

Table 1

Clinical and demographics features of the subjects.

ItemsAITDGDHTControls

Number1005629376781
Gender
 Male243 (24.18%)189 (30.05%)54 (14.36%)312 (39.95%)
 Female762 (75.82%)440 (69.95%)322 (85.64%)469 (60.05%)
Age (years)
Goiter
 No goiter290 (28.86%)132 (20.99%)158 (42.02%)
 Degree I258 (25.67%)166 (26.39%)92 (24.47%)
 Degree II408 (40.59%)289 (45.94%)119 (31.65%)
 Degree III49 (4.88%)42 (6.68%)7 (1.86%)
Family history
 (+)193 (19.20%)132 (20.99%)61 (16.22%)
 (-)812 (80.80%)497 (79.01%)315 (83.78%)
Ophthalmopathy
 (+)102 (10.15%)99 (15.74%)3 (0.80%)
 (-)903 (89.85%)530 (84.26%)373 (99.20%)

GD: Graves’ disease; HT: Hashimoto’s thyroiditis.