Research Article

Pressure-Controlled Ventilation-Volume Guaranteed Mode Combined with an Open-Lung Approach Improves Lung Mechanics, Oxygenation Parameters, and the Inflammatory Response during One-Lung Ventilation: A Randomized Controlled Trial

Table 1

Patients’ characteristics.

PCV+OLA
()
PCV
()
VCV+OLA
()
VCV
()

Age (years)0.185
Sex (F/M)19/2622/2222/2320/220.887
Height (cm)0.714
BMI (kg/m2)0.583
PBW (kg)59.62 ± 8.700.888
ASA (I/II/III)4/31/106/26/125/28/123/28/110.731
ARISCAT score
 Intermediate/high29/1628/1630/1522/200.527
Preoperative haemoglobin (mg/dL)133.60 (124.80, 144.40)137.55 (119.80, 144.40)131.00 (123.95, 140.80)138.20 (128.58, 145.88)0.583
Comorbidity
 Hypertension12 (26.7%)22 (50.0%)14 (31.1%)18 (42.9%)0.090
 Diabetes2 (4.4%)8 (18.2%)6 (13.3%)4 (9.5%)0.214
CVD10 (22.2%)4 (9.1%)4 (8.9%)6 (14.3%)0.215
Smoking
 No/current38/733/1132/1332/100.498
Creatinine (μmol/L)67.70 (60.95, 74.95)69.25 (59.13, 80.45)68.90 (61.70, 75.05)69.50 (63.68, 79.43)0.714
LEF (%)65.00 (62.00, 70.00)65.00 (61.00, 67.75)66.00 (63.00, 68.00)65.50 (61.75, 69.00)0.720
FVC (L)0.102
FEV1 (%)98.00 (89.00, 104.00)95.50 (82.95, 105.48)96.00 (80.50, 104.50)101.00 (89.00, 110.25)0.287
FEV1/FVC (%)0.632
Preoperative SaO2 (%)97.30 (95.85, 97.80)97.10 (96.20, 97.65)96.70 (95.95, 97.55)97.10 (96.28, 98.00)0.795

Data are expressed as (SD), numbers, or median (interquartile range). F: female; M: male; PBW: predicted body weight, calculated as follows: for women , for men ; ASA: American Society of Anesthesiologist; BMI: body mass index; CVD: coronary vessel disease; LEF: left ventricle ejection fraction; FVC: forced vital capacity; FEV1: forced expiratory volume in the first second; SaO2: oxyhaemoglobin saturation.