GCN2 Deficiency Enhances Protective Effects of Exercise on Hepatic Steatosis

Figure 2

Expression level of proteins involved in the GCN2/eIF2α/ATF4 pathway in the liver of mice: (a) representative immunoblot; (b–d) the expression levels of (b) GCN2, (c) phosphorylated eIF2α, and (d) ATF4 proteins. Data are (). ^§§ for the difference between sedentary and exercised WT mice groups, as determined by Student’s -test. and for the difference between sedentary and exercised regimes, as determined by two-way ANOVA and Tukey post hoc test. ^# and ^## for the difference between WT and GCN2KO groups, as determined by two-way ANOVA and Tukey post hoc test.

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