DMBA-Induced Oral Carcinoma in Syrian Hamster: Increased Carcinogenic Effect by Dexamethasone Coexposition

Figure 4

Macroscopic and corresponding microscopic images of OSCC development during DM-DMBA concomitant exposition (H&E stained). At 6, dysplasia and hyperkeratosis were evident. Around 12 weeks, papillomas were found macro- and microscopically. Finally, OSCC and multifocal neoplasias were developed on hamsters’ pouch.