Research Article

miR-1258 Regulates Cell Proliferation and Cell Cycle to Inhibit the Progression of Breast Cancer by Targeting E2F1

Figure 1

miR-1258 is poorly expressed in BC. (a, b) Volcano plots of DEmiRNAs and DEmRNAs in normal and tumor groups in the TCGA-BRCA dataset. Red dots indicate the upregulated miRNAs and mRNAs in BC, while green dots indicate the downregulated miRNAs and mRNAs. (c) Expression of miR-1258 in the normal and tumor groups in the TCGA-BRCA dataset. (d) Expression of miR-1258 in BC cells and breast epithelial cells. is compared to MCF-10A, .
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