A Prognostic Nomogram Based on Immune Scores Predicts Postoperative Survival for Patients with Hepatocellular Carcinoma

Table 2

Univariate analyses of the OS and DFS of hepatocellular carcinoma patients according to clinical pathological characteristics and immune scores.

		OS				DFS
Characteristics	Total	Alive	Dead	HR (95% CI)		Disease-free	Recurred	HR (95% CI)
Sex
Female	89	65 (28.02)	24 (35.82)	1.000		37 (26.81)	52 (32.30)	1.000
Male	210	167 (71.98)	43 (64.18)	0.824 (0.498, 1.364)	0.452	101 (73.19)	109 (67.70)	0.828 (0.595, 1.152)	0.262
Age (years)
≤30	13	12 (5.17)	1 (1.49)	1.000		4 (2.90)	9 (5.59)	1.000
31-40	16	12 (5.17)	4 (5.97)	1.222 (0.135, 11.070)	0.859	6 (4.35)	10 (6.21)	0.317 (0.127, 0.790)	0.014
41-50	36	28 (12.07)	8 (11.94)	1.594 (0.198, 12.810)	0.661	20 (14.50)	16 (9.94)	0.284 (0.125, 0.650)	0.003
51-60	88	69 (29.74)	19 (28.36)	1.747 (0.233, 13.080)	0.587	42 (30.43)	46 (28.57)	0.373 (0.182, 0.766)	0.007
61-70	99	80 (34.48)	19 (28.36)	1.438 (0.192, 10.780)	0.724	47 (34.06)	52 (32.30)	0.336 (0.164, 0.686)	0.003
71-80	44	29 (12.50)	15 (22.39)	2.146 (0.282, 16.340)	0.461	18 (13.04)	26 (16.15)	0.376 (0.175, 0.807)	0.012
>80	3	2 (0.86)	1 (1.49)	3.153 (0.197, 50.560)	0.417	1 (0.72)	2 (1.24)	0.418 (0.090, 1.948)	0.267
Grade		232	67
1	40	32 (13.79)	8 (11.94)	1.000		19 (13.77)	21 (13.04)	1.000
2	145	115 (49.57)	30 (44.78)	1.159 (0.531, 2.533)	0.711	70 (50.72)	75 (46.58)	1.197 (0.733, 1.954)	0.471
3	104	78 (33.62)	26 (38.81)	1.348 (0.609, 2.984)	0.461	44 (31.88)	60 (37.27)	1.267 (0.769, 2.086)	0.353
4	10	7 (3.02)	3 (4.48)	2.035 (0.534, 7.750)	0.298	5 (3.62)	5 (3.11)	1.253 (0.470, 3.341)	0.652
Stage
I	151	130 (56.03)	21 (31.34)	1.000		88 (63.77)	63 (39.13)	1.000
II	72	60 (25.86)	12 (17.91)	1.503 (0.783, 3.059)	0.261	29 (21.01)	43 (26.71)	2.171 (1.468, 3.209)	<0.001
III	72	40 (17.24)	32 (47.76)	4.379 (2.517, 7.617)	<0.001	20 (14.49)	52 (32.30)	2.928 (2.019, 4.246)	<0.001
IV	4	2 (0.86)	2 (2.99)	8.774 (2.038, 37.779)	0.004	1 (0.72)	3 (1.86)	8.832 (2.726, 28.620)	<0.001
Immune score
Low	30	19 (8.19)	11 (16.42)	1.000		8 (5.80)	22 (13.66)	1.000
Medium	61	46 (18.83)	15 (22.39)	0.456 (0.208, 0.997)	0.049	27 (19.57)	34 (21.12)	0.538 (0.314, 0.923)	0.024
High	208	167 (71.98)	41 (61.19)	0.289 (0.147, 0.570)	<0.001	103 (74.64)	105 (65.22)	0.381 (0.239, 0.606)	<0.001