Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS

<div>Representative chromatograms in negative ion mode: (a) a blank plasma sample; (b) a blank plasma sample spiked with parecoxib, valdecoxib, and IS; (c) a beagle plasma sample 3.0 h after injection of parecoxib.</div>

BioMed Research International

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Figure 2

Figure 2: Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS 