Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS

Table 5

Pharmacokinetic parameters of parecoxib and valdecoxib in group A and group B (, ).

Parameters	Parecoxib		Valdecoxib
	Group A	Group B	Group A	Group B
(h)
(h)
(ng/mL)
(L/kg)
(L/h/kg)
(ng·h/mL)
(ng·h/mL)