Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway

<div>IC50 values of the Saussurea costus extracts against cancer cell lines. The graph plotted between the percentage of viable cells of the cell lines MCF-7, HepG2, and HCT116 treated against the various concentrations (μg/ml) of extracts, viz., (a) methanol, (b) hexane, (c) chloroform, (d) ethyl acetate, (e) butanol, and the drug (f) doxorubicin. The percentage of viable cells was determined by SRB assay after 72 hours of treatment with an extract or the drug doxorubicin.</div>

BioMed Research International

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Figure 1: Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway

Figure 1 | Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway 