Research Article

Secondary Metabolites of Saussurea costus Leaf Extract Induce Apoptosis in Breast, Liver, and Colon Cancer Cells by Caspase-3-Dependent Intrinsic Pathway

Figure 3

Saussurea costus extracts induce apoptosis. The representative fluorescent images of the cancer cell lines (a) MCF-7, (b) HepG2, and (c) HCT116 treated with a plant extract for 48 hours and stained with AO/EB. (G) Bar graphs show the percentage of cells of a cell line in different stages of apoptosis after its treatment with a plant extract. Yellow arrow: live cell; green arrow: early apoptotic; red arrow: necrotic; purple arrow: late apoptotic.
(a)
(b)
(c)