Mechanism of YuPingFeng in the Treatment of COPD Based on Network Pharmacology
Table 5
Top 20 clusters with representative enriched terms (one per cluster).
GO
Category
Description
Count
%
Log10()
Log10()
hsa05200
KEGG pathway
Pathways in cancer
17
65.38
-24.08
-19.76
GO:0048545
GO biological processes
Response to steroid hormone
14
53.85
-18.36
-14.34
GO:0010035
GO biological processes
Response to inorganic substance
15
57.69
-17.79
-14.07
hsa05161
KEGG pathway
Hepatitis B
11
42.31
-17.79
-14.07
hsa05212
KEGG pathway
Pancreatic cancer
8
30.77
-14.63
-11.16
GO:0051090
GO biological processes
Regulation of DNA binding transcription factor activity
12
46.15
-14.15
-10.84
GO:0048608
GO biological processes
Reproductive structure development
12
46.15
-14.15
-10.84
GO:0050673
GO biological processes
Epithelial cell proliferation
12
46.15
-13.98
-10.75
hsa04933
KEGG pathway
AGE-RAGE signalling pathway in diabetic complications
8
30.77
-13.06
-9.94
GO:0097190
GO biological processes
Apoptotic signalling pathway
12
46.15
-12.44
-9.45
M197
Canonical pathways
PID HIV NEF Pathway
6
23.08
-11.88
-8.97
hsa05224
KEGG pathway
Breast cancer
8
30.77
-11.73
-8.87
GO:0060749
GO biological processes
Mammary gland alveolus development
5
19.23
-11.09
-8.36
GO:0030099
GO biological processes
Myeloid cell differentiation
10
38.46
-11.05
-8.34
hsa04066
KEGG pathway
HIF-1 signalling pathway
7
26.92
-10.95
-8.27
GO:0009410
GO biological processes
Response to xenobiotic stimulus
9
34.62
-10.9
-8.22
R-HSA-6785807
Reactome gene sets
Interleukin-4 and Interleukin-13 signalling
7
26.92
-10.75
-8.1
GO:0009314
GO biological processes
Response to radiation
10
38.46
-10.74
-8.1
hsa05416
KEGG pathway
Viral myocarditis
6
23.08
-10.44
-7.85
GO:0051384
GO biological processes
Response to glucocorticoid
7
26.92
-9.82
-7.34
“Count” is the number of genes in the user-provided lists that are associated with the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10()” is the value in log base 10. “Log10()” is the multitest-adjusted value in log base 10.
