The Effect of Grapefruit Juice on the Pharmacokinetics of Tadalafil in Rats

Figure 1

Representative HPLC for tadalafil and CBZ (IS) in rat plasma. (a) Blank plasma sample; (b) blank plasma sample spiked with tadalafil and CBZ; (c) rat plasma sample obtained 1.5 h after oral administration.

(a)

(b)

(c)