The LncRNA H19 rs217727 Polymorphism Is Associated with Oral Squamous Cell Carcinoma Susceptibility in Iranian Population
Table 5
The association of H19 polymorphism and OSCC susceptibility.
Inheritance model
Genotype
Cases (%)
Controls (%)
OR (95% CI)
value
rs217727
Codominanta
CC
110 (55)
133 (66.5)
CT
75 (37.5)
64 (32)
1.47 (0.93-2.15)
0.10
TT
15 (7.5)
3 (1.5)
6.04 (1.70-21.42)
0.001
Dominantb
CC
110 (55)
133 (66.5)
CT+TT
90 (45)
67 (33.5)
1.62 (1.08-2.43)
0.01
Recessivec
CC+CT
185 (92.5)
197 (98.5)
TT
15 (7.5)
3 (1.5)
5.32 (1.51-18.69)
0.003
Overdominantd
CC+TT
125 (62.5)
136 (68)
CT
75 (37.5)
64 (32)
1.27 (0.84-1.92)
0.24
rs2107425
Codominant
CC
79 (39.5)
74 (37)
CT
94 (47)
101 (50.5)
0.87 (0.57-1.33)
0.52
TT
27 (13.5)
25 (12.5)
1.01 (0.53-1.89)
0.97
Dominant
CC
79 (39.5)
74 (37)
CT+TT
121 (60.5)
126 (63)
0.89 (0.60-1.34)
0.60
Recessive
CC+CT
173 (86.5)
175 (87.5)
TT
27 (13.5)
25 (12.5)
1.09 (0.60-1.95)
0.76
Overdominant
CC+TT
106 (53)
99 (49.5)
CT
94 (47)
101 (50.5)
0.86 (0.58-1.28)
0.48
OR, odd ratio; CI, confidence interval. aCodominant, major allele homozygotes vs. heterozygotes. bDominant, major allele homozygotes vs. heterozygotes + minor allele homozygotes. cRecessive, major allele homozygotes + heterozygotes vs. minor allele homozygotes. dOverdominant, major allele homozygotes + minor allele homozygotes vs. heterozygotes.
