Expression of GLUT3 and HIF-1α in Meningiomas of Various Grades Correlated with Peritumoral Brain Edema

Figure 4

Hypoxia-inducible factor-1α protein (HIF-1α) nuclear immunostaining of meningioma cells. (a, b) High HIF-1α staining ((a) 40×; (b) 200×); HIF-1α strongly and diffusely expressed in meningioma cells (×40). (c, d) Moderate HIF-1α staining ((c) 40×; (d) 200×). (e, f) Low HIF-1α staining ((e) 40×; (f) 200×). Nucleus positive staining (black arrows) is evident in tumor cells. (a–d) are regarded as positive results, whereas (e, f) are regarded as negative results.

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