Research Article

Investigation of the Interaction Mechanism between Salbutamol and Human Serum Albumin by Multispectroscopic and Molecular Docking

Table 1

Binding constants and thermodynamic parameters of SBAL-HSA system at different temperatures.

T (K)K (L mol−1)ΔG° (kJ·mol−1 K−1)ΔS° (J·mol−1)ΔH° (kJ·mol−1)

288K1 × 1041.6121 ± 0.71−23.52 ± 0.85−93.53 ± 0.82−50.46 ± 0.76
3001.0886 ± 0.58−22.40 ± 0.92
3100.3472 ± 0.81−21.47 ± 0.73

288K2 × 1032.0094 ± 0.44−18.18 ± 0.25−31.41 ± 0.37−27.23 ± 0.29
3001.2214 ± 0.50−17.80 ± 0.32
3100.9001 ± 0.78−17.49 ± 0.54