Aspirin and Risk of Dementia in Patients with Late-Onset Depression: A Population-Based Cohort Study

Table 2

Characteristics of LOD patients with or without subsequent dementia ().

		Without dementia		With dementia		-value
		(81.2%)		(18.8%)
Age (years)	Mean (SD)	72.47	(5.64)	74.58	(5.81)	<0.001
Gender	F	2,785	(56.9)	673	(59.2)	0.156
	M	2,107	(43.1)	463	(40.8)
COPD	No	2,251	(46.0)	412	(36.3)	<0.001
	Yes	2,641	(54.0)	724	(63.7)
DM	No	3,056	(62.5)	663	(58.4)	0.010
	Yes	1,836	(37.5)	473	(41.6)
HTN	No	835	(17.1)	128	(11.3)	<0.001
	Yes	4,057	(82.9)	1,008	(88.7)
IHD	No	2,328	(47.6)	490	(43.1)	0.007
	Yes	2,564	(52.4)	646	(56.9)
CHF	No	3,555	(72.7)	785	(69.1)	0.016
	Yes	1,337	(27.3)	351	(30.9)
CVA	No	2,982	(61.0)	495	(43.6)	<0.001
	Yes	1,910	(39.0)	641	(56.4)
CRI	No	4,238	(86.6)	951	(83.7)	0.011
	Yes	654	(13.4)	185	(16.3)

CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CRI, chronic renal insufficiency; CVA, cerebrovascular accident; DM, diabetes mellitus; HTN, hypertension; IHD, ischemic heart disease; LOD, late-onset depression; SD, standard deviation. The t-test was used to comparing the means of age. Categorical variables (gender, COPD, DM, HTN, IHD, CHF, CVA, CRI) were compared using the Chi-square test between patients.