Aspirin and Risk of Dementia in Patients with Late-Onset Depression: A Population-Based Cohort Study

Table 5

Hazard ratios of aspirin use for risk of subsequent dementia in patients with LOD multivariate Cox proportional hazards model after matching by propensity score ().

	Hazard ratios	95% CI	-value
Aspirin
Yes vs. No	0.833	(0.708–0.981)	0.029
Age
Elder vs. younger	1.056	(1.042–1.0701)	<0.001
Sex
Female vs. male	1.063	(0.896–1.262)	0.485
DM
Yes vs. No	1.266	(1.072–1.495)	0.006
HTN
Yes vs. No	1.385	(1.032–1.787)	0.029
COPD
Yes vs. No	1.222	(1.028–1.452)	0.023
CRI
Yes vs. No	1.081	(0.862–1.357)	0.500
IHD
Yes vs. No	1.106	(0.934–1.309)	0.241
CHF
Yes vs. No	0.966	(0.825–1.204)	0.970
CVA
Yes vs. No	1.945	(1.649–2.294)	<0.001

CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CRI, chronic renal insufficiency; CVA, cerebrovascular accident; DM, diabetes mellitus; HTN, hypertension; IHD, ischemic heart disease; LOD, late-onset depression.