Serum Fibroblast Growth Factor 19 and Total Bile Acid Concentrations Are Potential Biomarkers of Hepatocellular Carcinoma in Patients with Type 2 Diabetes Mellitus
Table 2
Correlation analysis between Lg FGF19 and other parameters.
Control
T2DM
HCC
T2DM-HCC
r
r
r
r
Age
−0.215
0.282
0.176
0.381
0.168
0.533
0.056
0.877
BMI
−0.242
0.224
0.006
0.975
0.481
0.059
−0.390
0.265
FPG
−0.273
0.168
0.047
0.815
0.162
0.550
0.395
0.259
ALT
−0.152
0.451
−0.409
0.034
−0.068
0.802
0.145
0.690
γGT
−0.450
0.018
−0.042
0.836
0.536
0.032
0.357
0.311
ALB
−0.266
0.179
−0.371
0.057
−0.036
0.894
−0.104
0.774
TBA
0.400
0.039
0.477
0.012
0.684
0.003
0.673
0.033
TBIL
−0.363
0.063
−0.035
0.861
−0.103
0.704
0.010
0.978
eGFR
0.424
0.027
−0.005
0.980
0.062
0.819
0.047
0.898
Cys-C
−0.227
0.255
0.384
0.048
−0.058
0.833
−0.300
0.400
TC
−0.485
0.010
−0.070
0.728
0.026
0.923
−0.333
0.347
TG
−0.333
0.090
−0.229
0.251
−0.220
0.413
−0.064
0.861
LDL
−0.528
0.005
0.132
0.511
0.024
0.931
−0.079
0.828
AFP
0.001
0.998
0.140
0.486
0.540
0.031
0.560
0.092
CEA
−0.081
0.689
−0.091
0.650
0.078
0.774
0.464
0.177
Log-transformed variables; Pearson correlation analysis for normally distributed variables; Spearman correlation analysis for nonnormally distributed variables; control: healthy control; T2DM: newly diagnosed type 2 diabetes mellitus patients; HCC: newly diagnosed hepatocellular carcinoma patients; T2DM-HCC: type 2 diabetes mellitus combined newly diagnosed hepatocellular carcinoma patients. Total: total population. Abbreviations are same as in Table 1. values <0.05 were considered significant.
