Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on T Cell Differentiation in Primary Biliary Cholangitis

Figure 1

CD14⁺ monocytes were inducted to DCs. (a) The DC surface markers CD11c and CD14 were detected by FACS and the proportion of CD11c⁺ CD14⁺ DCs reached 97.2% after GM-CSF and IL-4 treatment. (b) Under microscope, the cells were irregular in shape, including stars, circles, and spindles, and the burrs process further increased and were in typical DCs morphology. (c) Under scanning electron microscope, the cell bodies showed an irregular shape and rough surface, and the microvilli on the cell surface disappeared and the lamellar plica was also visible.

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