Identification, Validation, and Functional Annotations of Genome-Wide Profile Variation between Melanocytic Nevus and Malignant Melanoma

Table 2

GO enrichment analysis of DEGs in the most significant module.

Term	Description	Count in gene set	value
GO:0007398	Ectoderm development	6
GO:0008544	Epidermis development	5
GO:0005198	Structural molecule activity	5
GO:0005200	Structural constituent of cytoskeleton	3
GO:0005856	Cytoskeleton	5
GO:0005882	Intermediate filament	3
GO:0045111	Intermediate filament cytoskeleton	3
GO:0043228	Non-membrane-bounded organelle	6
GO:0043232	Intracellular non-membrane-bounded organelle	6
GO:0001533	Cornified envelope	2
GO:0018149	Peptide cross-linking	2
GO:0031424	Keratinization	2

GO: Gene Ontology; DEGs: differentially expressed genes.