Anti-Inflammatory and Antioxidant Effect of <i>Eucommia ulmoides</i> Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-<i>κ</i>B Pathway

<div>EUP alleviates the increased expression of IRF-1, HMGB1, and TLR-4 caused by liver I/R. IRF-1 (a), HMGB1 (b), and TLR-4 (c) proteins detected by Western blot, and both HMGB1 (d) and TLR-4 (e) mRNA were quantified by RT-PCR. Compared with the I/R group, the expression of IRF-1, HMGB1, and TLR-4 in the high-dose EUP group was significantly decreased. 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BioMed Research International

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Figure 6

Figure 6: Anti-Inflammatory and Antioxidant Effect of <i>Eucommia ulmoides</i> Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-<i>κ</i>B Pathway 

Figure 6 | Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway 